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24-Nov-2017 12:51

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“It starts to turn on the tissue and very gradually self-destruct. For the heart it causes heart disease; for the brain it causes neurodegenerative diseases; for the gut it causes colonic carcinomas and other cancers.

There are nearly one million different components involved in the inflammatory response, and the strength of the response can depend on the genetic vulnerability of individuals.

The community who had stayed behind to fulfil the other tasks would have starved.” Loneliness has always been part of the human condition.

As our understanding of its negative effects has grown, so has our interest in it, leading to the emergence of a burgeoning loneliness industry.

There are apps to help you deal with loneliness; dating sites for friends; Spotify playlists; countless books. “It feels like being hungry: like being hungry when everyone around you is readying for a feast.

One of the most thoughtful explorations of the subject over the past year is Olivia Laing’s The Lonely City: Adventures in the Art of Being Alone. It feels shameful and alarming, and over time these feelings radiate outwards, making the lonely person increasingly isolated, increasingly estranged.

That’s the normal way our bodies get rid of something toxic.

But prolonged lack of social engagement can actually trigger a chronic background inflammation,” she says.

Another recent study, in the journal , found that socially isolated women had a 40 per cent higher risk of recurrence of breast cancer and a 60 per cent higher risk of dying.Rose Anne Kenny, professor of medical gerontology at Trinity College Dublin and a director of Mercer’s Institute for Successful Ageing, describes the unseen destruction caused by loneliness.“Our body responds to infection or any insult by inflammation.Video: Enda O'Dowd There is a condition that is twice as deadly as obesity and more dangerous than smoking 15 cigarettes a day.

It is a sneaky, capricious beast that can overwhelm you at 4am, as the world around you sleeps.After a recent decline in health Barbara is struggling to keep up an active social life, and is succumbing to loneliness.

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